Detection ofBRAFgene mutation in primary choroidal melanoma tissue

Bilateral primary choroidal melanoma.

A case of bilateral primary choroidal melanoma is described in a 51-year-old white male. Histological confirmation followed enucleation of the left eye and local excision in the right. A careful systemic evaluation failed to demonstrate any other primary or secondary melanomata. This case is the first bilateral primary choroidal melanoma reported in the United Kingdom and the first to be descri...

Coexistent primary choroidal and cutaneous melanoma.

Sir, The development of primary choroidal and cutaneous malignant melanoma in the same patient is rare, with only 8 cases described in the literature (1 – 3). In contrast, the occurrence of primary cutaneous and choroidal melanoma in association with the atypical mole syndrome has been documented by a number of authors (2). We describe here the case of a 71-year-old man who presented initially ...

Outcomes of primary endoresection for choroidal melanoma

Purpose To review long time treatment results in patients with small or medium sized choroidal melanoma who underwent surgical tumor endoresection as a primary treatment when plaque radiotherapy was unable and patients declined enucleation. Materials and methods Patients were evaluated for best corrected visual acuity (BCVA), and underwent biomicroscopy, indirect ophthalmoscopy, retinography ...

PET/CT imaging: detection of choroidal melanoma.

AIM To determine the size of untreated choroidal melanomas resolved by whole body positron emission tomography fused with computed tomography (PET/CT). METHODS 50 consecutive patients with untreated choroidal melanomas underwent whole body PET/CT. A functionally fused helical CT scan and 18-fluoro-2-deoxyglucose (FDG) PET scans were employed. The tumours were identified (both quantitatively a...

Choroidal Melanoma